updated 02/28/2014 AT 4:00 PM ET
•originally published 02/28/2014 AT 4:15 PM ET
Philip Seymour Hoffman died from acute mixed drug intoxication, the New York City medical examiner’s office announced Friday.
Heroin, cocaine, benzodiazepines and amphetamine were found in his system, said spokeswoman Julie Bolcer. His death was ruled an accident.
The first autopsy conducted on his body was ruled inconclusive earlier this month.
The Oscar-winning actor had struggled with drugs throughout his life, most recently checking into rehab for heroin in May after being sober for more than 20 years.