updated 04/13/2014 AT 11:00 PM ET
•originally published 04/13/2014 AT 9:50 PM ET
Jared Leto is on fire.
After a red carpet complete with costumed puppies and a cameo-filled intro by host Conan O’Brien, the MTV Movie Awards kicked off Sunday night – and just like the Golden Globes and the Oscars, the Dallas Buyers Club actor came away with a win.
Leto, 42, snagged a golden popcorn for best transformation. And as usual, the long-locked heartthrob couldn’t resist flirting with presenter (and fellow Oscar winner) Lupita Nyong’o, 31.
“It’s an award in itself to get that from her,” he cooed.
Check out the full list of MTV Movie Awards winners and their best acceptance speech quotes below!
Best On-Screen Transformation: Jared Leto, Dallas Buyers Club
Leto spoke of the AIDS epidemic and his hope that the disease will be eradicated soon. “Love who you want to love and live how you wish to live, and never let anyone stop you from turning your dreams into reality,” he said.