FIRST LOOK: Old and New Collide in Heroes Reborn – 'This Is Heroes on Steroids'

Oh, what a difference five years makes!

PEOPLE can exclusively premiere a First Look at NBC’s upcoming reboot Heroes Reborn, which finds many familiar faces from Heroes in the midst of a dangerous crisis – or, as creator Tim Kring puts it: “They are persecuted and hunted.”

Greg Grunberg's Son 90 Percent Better after Brain Surgery

Puberty is a tough time for anybody. For Heroes star Greg Grunberg’s son Jake, who has epilepsy, it presented its own unique challenges.

“Puberty screwed up levels of gauging whether his drugs were working or not. He was having more seizures,” Grunberg tells PEOPLE. “Hundreds a day.”

Heroes' Greg Grunberg: My Son Is My Hero

He’s played a CIA agent on Alias and now fights crime as a mind-reading police officer on Heroes. But Greg Grunberg says he’s not the star in the family.

“Jake is my hero, he really is,” Grunberg, 41, tells PEOPLE about his 12-year-old son, who has epilepsy. “He doesn’t let anything stop him, and to deal with everything with your head up high, that to me is a true hero.”

His son has been the inspiration behind his involvement in raising awareness about the neurological disorder, which includes raising funds for pediatric epilepsy research.

Hayden Panettiere to Sing with Greg Grunberg's Band

Heroes cheerleader Hayden Panettiere – who is also a budding singer – will make a guest appearance with fellow cast member Greg Grunberg’s all-star Band From TV this weekend, she confirms to PEOPLE.

“I sang with them at the wrap party for our show,” Panettiere, 17, told PEOPLE Tuesday at a party in L.A. celebrating NBC’s fall season. “I saw them and said, ‘Anytime you guys want me to perform with you I’m totally up for it.’ ”

Greg Grunberg's Mother's Day present for his wife

People_pg2Heroes star Greg Grunberg was busy baking some gigantic chocolate chip cookies on The Martha Stewart Show this morning while his wife of 14 years, Elizabeth, was en route to the city, under the impression she’ll be spending the weekend in the Big Apple.

UPDATE: Heroes' Greg Grunberg's charitable cause for his son

People_pg2Update: Greg has also created a Heroes Artwork Auction, where people canbid on autographed collector’s edition artwork from the show.

Heroes' Greg Grunberg Leads All-Star Band

Reading minds is a super power that really comes in handy for a down-on-his-luck cop like Matt Parkman, the role actor Greg Grunberg plays on NBC’s Heroes.

But in the real world, Grunberg, 40, is doing something powerful on his own: playing with an all-star band. Besides Grunberg on drums, there’s Desperate Housewives’ James Denton on guitar, House’s Hugh Laurie on piano and The Bachelor’s Bob Guiney as singer, among others.