#TBT: The Top Grey's Anatomy Pilot Moments

Oftentimes, it takes a few episodes to get really invested in a show. But from its 2005 premiere date, Grey’s Anatomy sucked us in. In honor of the show’s 10-year anniversary (and Thursday’s new episode!), let’s look back at the best moments from the show’s pilot for an epic game of remember when …

Grey's Anatomy's Best 'Oh' Faces for Saying Goodbye to Cristina Yang

For 10 years Sandra Oh has brought the sassy, snarky Cristina Yang to life on ABC’s Grey’s Anatomy, but after a decade watching the no-nonsense doctor, it is time to say goodbye.

Here are some of the best “Oh” faces from over the years to help you through the stages of grieving Cristina’s departure.

Relive Sandra Oh's Best Grey's Anatomy Moments

After 10 seasons saving lives at Seattle Grace, Dr. Cristina Yang is saying goodbye to Grey’s Anatomy.

Grey's Anatomy's Cristina Yang 'Deserves Better'

Isaiah Washington, absent from Grey’s Anatomy since the end of season 3, made a controversial return to the ABC hit Thursday night, two episodes before the season will end with Dr. Cristina Yang (Sandra Oh) exiting the show.

Laura Prepon Is Leaving Orange Is the New Black

Laura Prepon has flown the coop.

Orange is the New Black, the Netflix original series that takes place in a women’s prison, will lose one of its central characters, inmate Alex, played by Laura Prepon, according to the Hollywood Reporter.

Sandra Oh Is Leaving Grey's Anatomy

She’s hanging up her scrubs for good.

Next season will be the last for Grey’s Anatomy star Sandra Oh, after what will be 10 seasons on the hit ABC medical drama.

“It’s been a great privilege to play the character of Cristina Yang on GA, and I am both sad and excited to see where this, her final season will take her,” Oh, 42, said in a statement, EW.com reports.

Grey's Anatomy: Getting Out of Africa

“It’ll be an easy day.” That’s what Owen promised wife Cristina early in Thursday’s Grey’s Anatomy, which naturally, meant the day would turn out to be anything but. Stormy, life-altering – those would’ve been more appropriate descriptions. By the time the episode ended, one couple had broken up, two friends were at odds and a doctor had decided to quit the hospital.

Grey's Anatomy Recap: What Honeymoon Phase?

Thursday’s Grey’s Anatomy began on the stormy morning after Cristina and Owen’s wedding, with the bride waking up in a panic next to her new husband. She was married! Owen seemed prepared for a freak-out and encouraged his wife to stay calm. “We’re just gonna get up and go to work like always,”he said casually, handing her a multigrain bar and tenderly offering to shampoo her hair.

SPOILER! Grey's Anatomy Wedding Secrets Revealed

After surviving the shooter rampage that claimed the lives of two doctors at Seattle Grace Hospital on the season finale of Grey’s Anatomy, Cristina (Sandra Oh) and Owen (Kevin McKidd) realize that life is too precious – and will tie the knot during the show’s Sept. 23 premiere on ABC.

Katherine Heigl Hosts Ellen Pompeo's Baby Shower

Mom-to-be Ellen Pompeo was joined by 25 friends, including Kate Walsh, Sandra Oh and Rebecca Gayheart, for a baby shower held Saturday afternoon at Katherine Heigl’s home in the Los Feliz section of Los Angeles.

Pompeo and her husband Chris Ivery are expecting a baby daughter in October.