updated 04/28/2010 AT 10:55 AM ET
•originally published 04/28/2010 AT 8:30 AM ET
When you’re the World’s Most Beautiful Woman, there are a few things to always remember before leaving the house: Brush your teeth. Don’t take longer than the kids to get ready. And leave certain things (hair color and waxing) to trained professionals. Or so says Julia Roberts in an exclusive Q&A to celebrate her fourth turn as the cover girl for PEOPLE’s Most Beautiful issue.
Though it’s hard to believe it’s been 20 years since Roberts starred in Pretty Woman, her relaxed vibe about beauty has served her well over the years. “She’s never looked more beautiful,” says Ryan Murphy, the director of her upcoming film, Eat, Pray, Love, based on the huge bestseller. “She is so happy and fulfilled and it shows.”
At 42, the mom of three (twins Hazel and Phinnaeus are 5 and Henry is 2) signed her first beauty contract in January to become Lancome’s global ambassador. “It’s fun to find myself with this type of new career at my advanced age!” she writes about the gig, in the issue on newsstands Friday.