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As Dan Wiesel and Alysa Binder boarded their flight from San Francisco to Florida, they were worried. Not about themselves, but about their Jack Russell Terrier Zoe, flying alone in the cargo hold below their cabin. They decided there had to be an easier, more comfortable way for their pet to fly, so they developed their own solution: Pet Airways.

Launching in July, the animal-friendly airline is open to furry creatures only: No people allowed (minus pilots and pet attendants, of course). The Beech 1900 planes fly in and out of regional airports in New York, Washington, D.C., Chicago, Denver and Los Angeles, delivering dogs and cats for just $149 each way. Owners drop their pets at a Pet Airways airport lounge, and pick them up straight from the plane upon arrival (they can even track them online). Pet Attendants ensure animals' comfort, even monitoring how often the little guys relieve themselves. Any size dog or cat is welcome, and soon, the airlines will open up to reptiles, birds and pigs (and eventually, more cities). Now that's creature comfort!